Microfluidic controller CubiX

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he only microenvironment controller fully compatible with live imaging. It enables mimicking physiological and pathological culture conditions in vitro. Scalable, highly customisable and user-friendly. CubiX platform includes a control unit (software, gas & flow controller), a heating stage & microfluidics perfusion lid(s). Hypoxia and/or normoxia Long term cell culture (>15 days) Compatible with primary cells Real-time monitoring (pH, lactose, glucose, O2) Applications DIFFERENTITATED ENDOTHELIUM HIGH THROUGHPUT ORGANOIDS IN A WELL FULLY DIFFERENTIATED VASCULARIZED & IMMUNOCOMPETENT SKIN FULLY DIFFERENTIATED SKIN & METASTATIC MELANOMA BLOOD BRAIN BARRIER 3D LIVER CO-CULTURE Step 1: Set Up The Parameters Configure temperature, oxygen, flow rate, and pH levels for the CubiX microphysiological system to create the desired experimental conditions. Step 2: Secure The Perfusion Lid Transform the standard multiwell configuration into a perfusion dynamic system by securely closing the perfusion lid. Step 3: Click And Play Easily switch between up to 4 different experimental conditions with simple clicks, allowing seamless experimentation. Step 4: Live Imaging And Data Acquisition Observe and collect real-time data through live imaging to monitor the physiological responses and outcomes of the experiments and drug testing performed in CubiX. Control Unit Manipulate the parameters following the experiment condition Medium Enrichment Long-term experiments, <4 medium compositions External culture medium receiver For long-term experiments, < 4 medium compositions Heating Stage Temperature control Microfluidic Perfusion Lid