These bioactive composite bone graft matrices are a combination of three components: Carbonate Apatite anorganic bovine bone mineral, 45S5 Bioactive Glass, and Type I Collagen. This trio provides a uniform distribution of bioactive glass and mineral particles throughout the matrix so that the bone graft is steadily resorbed and replaced by new bone formation.
Advantages of 45S5 Bioactive Glass
Favorable Environment
for bone regeneration and osteoblast attachment.
Ion Exchange & Release
including soluble tetrahedral silica, which may promote rapid bone formation.
Cell Proliferation & Differentiation
45S5 Bioactive glass has the ability to stimulate the growth & osteogenic differentiation of human primary osteoblasts8.
BENEFITS OF CARBONATE APATITE
• Optimal Resorption & Remodeling
• Natural Mineral Structure Similar to Human Bone Mineral
• More Calcium Phosphate Deposition Than βTCP4
• Half the crystallinity than HA, More Soluble
• Independent Studies have shown Higher Osteoclastic & Osteoblastic Activity than βTCP & HA6