CDC: «Carbapenem-resistant Enterobacteriaceae (CRE) are usually resistant to all β-lactam agents as well as most other classes of antimicrobial agents. The treatment options for patients infected with CRE are very limited. Healthcare-associated outbreaks of CRE have been reported. Patients colonized with CRE are thought to be a source of transmission in the healthcare setting. Identifying patients who are colonized with CRE and placing these patients in isolation precautions may be an important step in preventing transmission».
CHROMagar™ launched in 2007 the first chromogenic medium for the detection of carbapenem-resistant bacteria, particularly targeting KPC-enzymes. Since then, many other carbapenemases have been spreading around the world and therefore there was a need to address today the difficult detection of low level carbapemases.
Alain Rambach and Patrice Nordmann have joined their efforts to develop a highly sensitive chromogenic medium, CHROMagar™ mSuperCARBA™, the new generation of chromogenic media that reaches unprecedented performances: detection of a large variety of carbapenemases KPC, NDM, VIM, IMP, OXA…with an impressive limit of detection (10 CFU/mL) even for weakly expressed carbapenemases like OXA-48, while maintaining a high level of selectivity.
Intended Use :
CHROMagar™ mSuperCARBA™ is a selective and differential chromogenic culture medium, intended for use in the qualitative direct detection of gastrointestinal colonization with carbapenem-resistant Enterobacteria (CRE), including OXA-48 producers, to aid in the prevention and control of CRE in healthcare settings.