Solution reagent CNGSDx-0050

for PCRdiagnosticNGS

Next Generation Sequencing (NGS) has revolutionized molecular diagnostics with its capacity of massive parallel sequencing of DNA or RNA fragments to detect clinically important genomic variants and mutations. A critical step in generating high-quality NGS data is the preparation of pure DNA or RNA of specific lengths. To support this, we offer CleanNGS Dx for library cleanup and size selection, ensuring the highest levels of precision and consistency in your diagnostic workflows. Our special buffer formula ensures optimal size selection for NGS libraries, and the high-quality magnetic beads allow faster separations and better RNA/DNA recovery. CleanNGS Dx is produced RNase free, which makes it an ideal solution for all downstream RNA or DNA NGS experiments. Benefits Easy automation DNA and RNA Suitable for PCR/NGS Fast and Eefficient For use in diagnostic workflow Applications CleanNGS Dx is suited for cleanup in between NGS library preparation steps, or post library preparation for size selection, in diagnostic workflows. For double sided size selection, we first add CleanNGS Dx reagent with magnetic beads in a certain volume ratio. Separate the large DNA or RNA fragments from the solution with a magnetic plate and add more CleanNGS Dx reagent to the supernatant to clean up the small DNA fragments and inhibitors. After two washing steps, the purified DNA or RNA is eluted.