The Ioflupane I-123 radiopharmaceutical production line is a highly automated plant for dispensing batches of 500 vials at a speed of 360 vials per hour.
Number of working chambers:
12
Type of process:
“Aseptic manufacturing”
Type of shielding:
Lead 75mm / Lead 50mm / Lead 30mm
Automation systems available:
Automatic synthesis and purification of 123I Ioflupane by HPLC process
Automatic vial filling machine, including vial stoppering, capping and crimping, 100% weight control
Dispensing mode in open and closed vials
Automatic buffer for 500 vials
Semi-automatic Visual Inspection (VI)
Automatic vial and shielded container labelling
Automatic vial discharge in automatic container
Particularly interesting features:
Management and development of HPLC purification in automatic
Scale up and process chemistry development
Automatic bulk formulation management
Decontamination with VPHP
Format changeover management with considerable reduction in operator radio-exposure
Semi-automatic visual inspection of radioactive product
Productivity:
6 vials / minute in dispensing (filling 2,5ml)
4 vials / minute in VI, labelling and packaging.