Aspartate aminotransferase (ASAT, AST, GOT) is an enzyme widely present in tissue especially liver, heart and skeletal muscle Determinations of elevated ASAT activity in serum and plasma are mainly used to aid in the diagnosis and monitor of liver diseases e.g. hepatitis, hepatic cirrhosis, drug-induced liver injury, hepatic metastasis, mononucleosis. Also skeletal muscle diseases such as muscle trauma, surgery, burns, muscular dystrophy, heat stroke and other diseases such as acute hemolytic anemia, acute pancreatitis and patients with higher risk of COVID-19 adverse outcome. Decreased levels of ASAT can be observed in acute renal disease, beriberi, diabetic ketoacidosis, pregnancy, chronic renal dialysis.
Specification
Method according to International Federation of Clinical Chemistry (IFCC), without pyridoxal phosphate
Specimen serum
On board stability up to 12 weeks
Calibration stability up to 12 weeks
Measuring range linear up to 1200 U/l
Regulatory status CE IVD