Enzyme reagent

clinicalblood samplefor clinical chemistry

Creatine kinase (CK) catalyzes the transfer of phosphate group between creatine phosphate and adenosine diphosphate (ADP). Determinations of creatine kinase activity in serum are used to diagnose and monitor muscular injuries. It is also used as an aid in diagnosis of clinical conditions associated with abnormal creatine kinase activity. Increased creatine kinase activity can be observed in myocardial infarction, viral myositis, polymyositis and other muscle inflammations, muscular dystrophy, malignant hyperthermia, acute rhabdomyolysis, muscle injuries, circulatory disorders, overactive thyroid gland or kidney failure. High creatine kinase activity may also occur in infectious diseases (e.g. typhoid fever), prostate, kidney, ovary and gallbladder cancers, after surgical procedures and in damage of the muscle tissue as a consequence of intense training. Specification Method optimized kinetic, according to the International Federation of Clinical Chemistry (IFCC) Specimen serum On board stability up to 12 weeks Calibration stability up to 12 weeks Measuring range linear up to 3100 U/l Regulatory status CE IVD