Gamma-Glutamylotransferase (GGT) is an enzyme primarily found in liver. Determination of GGT activity in serum or plasma is mainly used as an aid in diagnosis and monitoring of acute and chronic diseases of the liver, bile ducts and pancreas. A significant increase in the activity of the enzyme is observed in such liver diseases as: cancer, alcohol damage, cirrhosis, inflammation (both acute and chronic). It is also a sensitive indicator of inflammation of the bile ducts or the gallbladder. Measurement of GGT activity is used to monitor abstinence in alcoholics during drug addiction treatment and to monitor the hepatotoxicity of drugs in chemically treated cancer patients.
Specification
Method according to the International Federation of Clinical Chemistry (IFCC), kinetic with L-γ-glutamyl-3-carboxy-4-nitroanilide
Specimen serum, plasma
On board stability up to 12 weeks
Calibration stability up to 12 weeks
Measuring range linear up to 1200 U/l
Regulatory status CE IVD