LE220Rsc Focused-ultrasonicator
High-performance, Scalable, Automated Sample Preparation
As the highest power and fastest sample processing system in the Covaris portfolio, the LE220Rsc rapidly delivers AFA-energetics® to standard SBS format plates using the scanning mode. It offers tunable acoustic energy, integration with robotic platforms, and more power than the LE220-plus and R230 Focused-ultrasonicators. This instrument enables a variety of novel high power, fast process applications such as lysis of difficult to lyse microorganisms (for example, yeast) in a 384 well plate and dissolution of difficult to solubilize compounds.
Feature
Automated workflows with full robotic integration
Powered by AFA-energetics
Multiple isothermal energy delivery modes
Broad temperature range at high power
Benefit
Accurate, reproducible, and robust sample preparation
Versatile
High-throughput
Tuneable, non-contact processing
Multiple sample types
Compatible with most processes
Simplify highly complex workflows
Multiple applications: nanoparticle formulation, microbe lysis, and hydrophobic compound dissolution
Supported Applications:
DNA/Chromatin shearing
Cell Lysis: mammalian, bacterial, yeas
Biomolecule extraction: FFPE, tissue, and whole blood
Sample processing: bead mixing
Compound screening
Hit validationTarget ID & validation
Fully Automated NGS Library Preparation Workflow
The LE220Rsc Focused-ultrasonicator aids in the movement of samples through numerous steps in a workflow on multiple instruments without human intervention. Processing time for a 96 and 384 plate ranges from 5 to 16 minutes, depending on desired fragment size.