Cytotoxicity assays measure the toxic effects of various cytotoxic drugs or physical stressors on cells. C.LIVE Tox reagents directly and reliably identify cytotoxicity in real time through an easy mix-and-read workflow. They are sensitive DNA- binding dyes that are nonpermeable to viable cells and nonfluorescent outside of the cells. After entering dead cells through damaged plasma membranes and binding to DNA, the reagent emits bright fluorescence. The growth and morp
Key Features & Benefits
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Direct detection of dead cells
Identify cell death the moment it happens using real-time monitoring inside your incubator.
Optimized for long-term cell studies
Manipulate periods, intervals, and time frames to fit your schedule
Easy mix-and-read workflows
Plate, add, and image in three easy steps with our reagents
Kinetic monitoring of cytotoxicity
Measure fluorescent objects over time with ease and confidence.
Product Details
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Observe real-time cytotoxicity
analysis in your incubator
Use the CELLCYTE X to image and quantify fluorescent signals of your cytotoxicity assay without removing the cells from the incubator. HeLa cells were treated with increasing concentrations of Staurosporine. C.LIVE Tox Green was added to each well (250 nM) and time-lapse images were obtained with the CELLCYTE X. The control well shows minimal green signal compared to Staurosporine-treated well at 48 hours (left panel). Automated quantification shows the time- and dose-dependent toxicity effects of Stau-rosporine (right panel).
Product
Applications
Accelerate your research
Cytotoxicity
Cell health & death