ANTI-B (ABO2) is used for blood grouping. It enables determination of the presence of erythrocytic antigen B on the human red blood cells surface. The reagents are prepared from monoclonal antibodies in a storage medium. The monoclonal antibodies, IgM type, produced by DIAGAST are derived from the supernatants of in vitro cultures of hybridomas of murine originQuantity: 5 x 10 mlClones:9621A8
Blood grouping is the determination of the presence or absence of ABO and RH1 (D) antigens.
Blood group determination is performed in 2 steps:
Forward typing, where the presence of antigens on the surface of Red Blood Cells (RBC) is investigated with known antisera (
Reverse typing, where the presence of anti-ABO antibodies in the plasma is investigated with known antigens (commercial RBC)
The agreement between forward and reverse typing is a sine qua non condition for the determination of a blood group.
DIAGAST produces monoclonal antibodies and RBC for the forward and reverse typing, respectively.