WBP is an acronym for Whole Body Plethysmography. WBP is a way to measure respiratory function in animals (or people) without the use of anesthesia or restraint. The system relies on a specially designed chamber in which the subject is placed. A sensitive pressure transducer is connected to measure pressure changes inside the chamber. Since the chamber is fitted with screen pneumotachs which allow air to pass outside the chamber, the small pressure changes in the chamber are related to flow. And so, the chamber is a plethysmograph. From these small flows signals, utilizing special algorithms Buxco FinePointe software derives ventilatory and bronchio constriction parameters.
Key Features:
Species: Mouse, Mouse Pup (P3 and older), Rat, GP and other species up to 1kg.
For larger animals refer to Large Animal WBP page
Up to 16 animals configured using 2 site or 4 site hardware controllers
Integrated, automated, software regulated bias flow
Pre-calibrated digital temperature and humidity
Integrated nebulizer controller per channel for simultaneous exposure
Integrated 4-port gas automation
Detachable control console for equipment setup flexibility (4-Site only)
Automated calibration for up to 4 chambers with a single click
Automated microprocessor-controlled system diagnostics
Combination Studies - option to integrate fluid swivels, electrical commutators, and optogenetics (LED)