Similar to spirometry in cooperative humans, the Buxco® pulmonary function testing system provides comprehensive PFT data for pre-clinical applications. For the functional residual capacity (FRC) test, subjects must be spontaneously-breathing. For other tests, subjects may be ventilated (ventilator included) or spontaneously-breathing. Subjects are anesthetized and the tests are automated.Features• Most comprehensive assessment of the lung• Complete a series of tests in just minutes• View results immediately, use overlays to compare repeated tests• Ideal for chronic obstructive pulmonary disease (COPD) studies• Determine FRC and other lung capacities• Software reports forced expiratory volume (FEV), forced expiratory flow (FEF) and many other values• Direct measurement of pulmonary mechanics—lung resistance and dynamic compliance• Reports produce group average of P-V loops and F-V loops