Small animal plethysmograph Buxco® FinePointe

for animal research

RC is an acronym for Resistance and Compliance. Resistance and Compliance is the original technique for evaluating lung function. By measuring lung pressure and airway airflow, lung function can be likened to a balloon with a tube through which air can enter and exit the balloon. Using this analogy, the single compartment lung model can be solved with related air flow and air volume to pressure across the lung. DSI’s Buxco® FinePointe Series Resistance and Compliance (RC) sites provide the hardware necessary to collect invasive resistance, dynamic compliance, and elastance data in anesthetized animals. This system is adaptable to different measurement models that include options for evaluating spontaneously breathing, ventilated, aerosol challenged, and IV challenged animals. Airway measurements can be relative to atmospheric pressure or esophageal pressure, the later allowing for transpulmonary pressure changes to be measured. Key Features Species: Mouse, Rat, Guinea Pig Continuously measure lung resistance and dynamic compliance in anesthetized animals In-line aerosol delivery and control Built-in console enables control from the site location Supports intubated animals for longitudinal studies Single USB connection to computer Live display and monitoring of the signals and derived data Software supports up to 8 simultaneous subjects Optional static compliance measurement available Optional heart rate or blood pressure monitoring