Toxoplasmosis test kit ELI.H.A Toxo

IgGIgMToxoplasma gondii

ELI.H.A Toxo enables the quantitative determination, by indirect hemagglutination, of serum antibodies (IgG and/or IgM) present in patients suffering from toxoplasmosis (Toxoplasma gondii). Results in International Units Liquid ready-to-use reagents Cost-effective test High sensitivity and specificity Simple visual reading, without expert interpretation Benefits Intended use Toxoplasmosis is a parasitic disease caused by the protozoan Toxoplasma gondii. Benign or asymptomatic in most of cases, it presents a serious risk for pregnant seronegative women and subjects with a weakened immune system. ELITech developed the ELI.H.A Toxo, an indirect hemagglutination assay, for the quantitative determination of anti- Toxoplasma gondii antibodies (IgG and/or IgM) in the serum. It is rapid, easy-to-use and easy-to-read with results available within 2 hours and reliable overnight. Principle Sheep red blood cells are sensitized with Toxoplasma gondii antigen. IgM as well as lgG antibodies are detected by this technique. They can be differentiated by treating serum with 2-mercaptoethanol (2-ME), which inhibits the agglutinating power of IgM. Diluted serum is mixed with sensitized sheep red blood cells. If anti- Toxoplasma gondii antibodies are present in the serum, sensitized red blood cells will agglutinate, resulting in a cloudy red/brown deposit coating the well. In the absence of specific antibodies, sensitized red blood cells will not agglutinate, resulting in a ring-like deposit at the bottom of the well.