Tuberculosis is a major and underdiagnosed health issue commonly caused by species belonging to the Mycobacterium tuberculosis. The steady increase of resistant forms, caused by intensive use of frontline antibiotics such as rifampicin and isoniazid, is particularly alarming and leads to massive treatment failure. Rapid and reliable detection of patients infected with MTB and resistance to rifampicin and isoniazid, is essential to determine the right therapy and limit the use of inappropriate treatments. MDR/MTB ELITe MGB® Kit is a real-time PCR assay designed for the simultaneous detection of the DNA of Mycobacterium tuberculosis complex and resistance to rifampicin and isoniazid. The assay is validated in combination with ELITe InGenius®, a fully automated sample-to-result solution.
Benefits
Conserved targets
MTB Complex: IS6110 region repeated sequence
Rifampicin resistance: rpoB gene hotspot region
Isoniazid resistance: katG gene and inhA gene regions
Internal control: artificial DNA sequence
Easy-to-use
Monoreagents, ready to use
Best-in class PCR technology
ELITe MGB® probes designed with Minor Groove Binder technology, Superbases® and Eclipse® Dark Quencher
Integrated workflow
Fully automated process for extraction, amplification and result analysis with ELITe InGenius
Eluate storage -
Additional testing including multiple PCR from the same eluate, retesting or archiving
Complete respiratory infections menu -
Complete respiratory infections range with Aspergillus spp ELITe MGB® Kit, Pneumocystis ELITe MGB® Kit, Respiratory Viral ELITe MGB® Panel and Respiratory Bacterial ELITe MGB® Panel