Genetic disorder test kit ELITe MGB®

coagulationfor geneswhole blood

Factor V, Factor II, and Methylene Tetrahydropholate Reductase (MTHFR) genes are involved in the coagulation system. Single nucleotide polymorphism variants (SNP) of those genes are associated with higher risk of thrombosis and embolisms. Variant detection by genetic testing is important in patients with hypercoagulability to provide adapted therapy. Coagulation ELITe MGB® Kit is a real-time PCR assay designed for the detection and the allelic discrimination of the main variants associated with thrombosis and embolisms: Factor V G1691A (Leiden), Factor II G20210A and MTHFR C677T. The 3 variants are detected in one single reaction by melt-curve analysis. The assay is CE-IVD validated on blood samples, in combination with ELITe InGenius®, a fully automated sample-to-result solution. Benefits Conserved targets - Factor V: single nucleotide polymorphism G1691A Leiden region Factor II: single nucleotide polymorphism G20210A region MTHFR: single nucleotide polymorphism C677T region Easy-to-use - Monoreagent, ready-to-use Best-in class PCR technology - ELITe MGB probes designed with Minor Groove Binder, Superbases® and Eclipse® Dark Quencher Integrated workflow - Fully automated process for extraction, amplification and result analysis with ELITe InGenius Eluate storage - Additional testing including multiple PCR from the same eluate, retesting or archiving