emkaBATH is a type of tissue bath setup, designed for contractile measures in tissues such as aortic, tracheal, iliac, and papillary muscles, and/or microvessels such as veins, small arteries, and lymph vessels. The system provides heated, oxygenated, and nutrient-rich perfusate to the tissue with or without drug administration and electrical stimulation.
Tissue baths are widely used to study the effects of agonists and antagonists on tissue contractility. Dose-response curves allow for characterization of a drug’s pharmacological profile and the calculation of EC50 or Emax.
Applications
Safety Pharmacology
Heart failure & Cardiac Model development
Vascular biology
Asthma & Airway Hyperresponsiveness
Pulmonary Fibrosis
Tobacco & Cannabis Studies
Techniques & Measurements
Isometric tissue contraction
Features & Benefits
Modular
Easy to use
Reproducible