CMV Screen is an ELISA test designed for quantitative determination of anti-Cytomegalovirus (CMV) immunoglobulins (total Ig) based on the principle of analysis by competition.
Clinical Significance:
Cytomegalovirus is a herpes virus transmitted by close human contact. No symptoms of infection are apparent in the majority of cases. However, the virus is very dangerous and may be fatal in immunosupressed patients. Serum-negative female patients who become infected during pregnancy may transmit the disease to the fetus. In 95% of cases this occurs without symptoms, but some neonates may present jaundice, hepato-splenomegaly and retarded psycho-motorial development. For this reason it is of great importance to determine the immunitary state of the patient and check for serum conversion, particularly for transfusion purposes.
Technical Specification
Test Quantitative
Wavelength 450 nm or 450/ 620 nm