IonFlux provides the highest degree of control over fluidics for specialized ion channel assays. With its unique microfluidic plates, IonFlux is the only system where all cell recordings and liquid exchange are performed within the plate proper. Without the hindrance of liquid handlers, the system advances high throughput ion channel experiments by providing unique attributes that permit specialized assays, impossible or impractical using other asynchronous systems:
Parallel and rapid exchange of solution
Continuous flow of extracellular solutions and compound throughout the whole experiment.
High Quality recordings from 16 or 64 amplifier channels
Available temperature control with positive feedback
The specialized characteristics related to its unique liquid exchange permits IonFlux to perform ligand binding, allosteric modulation, multiple agonists, and voltage- and temperature-sensitive assays with flexibility and ease. Complex ligand-gated assays, requiring serial exchange of solutions, can now be screened at the same speed and ease as voltage-gated assays.