Enzyme reagent INNOTEST®

for researchHIV

INNOTEST HIV Antigen mAb is an enzyme immunoassay for the qualitative detection of HIV p24 antigen in human serum, plasma, and cell culture supernatant. Features & Benefits User-friendly assay: High sensitivity: 10 pg/mL in serum Optimal specificity: 99.9% (after retesting) Detects all known HIV strains Low sample volume: 100µL Results in just 2 hours Neutralization reagents available (Article no. 80565; CE; 2 vials). The INNOTEST HIV Antigen mAb Neutralization Reagents kit contains reagents for confirmation of HIV p24 antigens in repeatedly reactive samples. Additional protocols (available upon request) Protocol for working with cell culture supernatants* Protocol for making Ag/Ab dissociation reagents* Protocol for RUO quantification of p24 antigen* * For research use only. Not for use in diagnostics procedures. Background The human immunodeficiency virus (HIV) is recognized as the etiological agent of acquired immune deficiency syndrome (AIDS). The virus is mainly transmitted by sexual contact, mother-to-child transmission, use of contaminated injection needles, and transfusion of contaminated blood. HIV/AIDS is one of the most important global illnesses. According to figures published in the UNAIDS/WHO 2006 AIDS Epidemic Update, an estimated 39.5 million people are living with HIV. There were 4.3 million new infections in 2006 with 2.8 million (65%) of these occurring in sub-Saharan Africa and important increases in Eastern Europe and Central Asia, where there are some indications that infection rates have risen by more than 50% since 2004. In 2006, 2.9 million people died of AIDS-related illnesses.