Bw4/Bw6 ambiguities can be resolved by an additional Bw4-specific amplification and hybridization on one strip.
INNO-LiPA HLA-B Update Plus is a line probe assay for the molecular typing of human leukocyte antigen (HLA) B alleles at allele group level (B*07 – B*83).
Details
Features & Benefits
More informative than serology
INNO-LiPA HLA-B Update Plus yields more information on genetic variation
New alleles mainly appear as new probe patterns, not blanks
Null alleles can be detected
Convenient
Reagents are synthesized and are therefore not limited in quantity
Reagents are standardized to show minimal batch-to-batch differences
INNO-LiPA HLA-B Update Plus utilizes DNA samples that are easy to transport
Cell viability or surface expression is not important
Two to three strips replace multiple testing
Rapid
INNO-LiPA HLA-B Update Plus can be used for emergency typing as well as for large batch analysis
One technician – one to one hundred samples – one working day
Simple
The LiPA technique is easy to perform
Automation is possible using TENDIGO® and Auto-LiPA™ 48
Objective interpretation of data with LiRAS® for LiPA HLA software