Granulator for the pharmaceutical industry Gral™

high-shearhigh-speed

The GEA top-drive high shear granulator range are multi-purpose processors, equally suitable for the high speed dispersion of dry powders, aqueous or solvent granulations, effervescent products and melt pelletization. With the Gral range, GEA pioneered the top-driven High Shear Granulators. Two versions of the top-driven high shear granulator are available: Gral and UltimaGral. Unique process design The key to success is the unique design of vessel and mixing tools. The angled position of the mixing blades combined with the rounded edges at the bottom of the vessel guarantee the typical rope-type movement for optimal flow of product during granulation. Several binder liquid spray systems are available to suit your process. Bowl and mixing blades are shaped and mounted to minimize clearance for maximum yield, without locally overheating the product. During a discharge cycle, the centrifugal force created by the rotation of the mixing arm will push the product in a natural way to a proportionally regulated outlet valve at the side without compacting the wet granules. This way we can accurately dose the finished granules to a calibration unit, connected to the outlet. GEA Pharma is the perfect partner for the development of a granulation process from formulation up to full-scale production. With capacities from 10 to 1200 liter, the (Ultima)Gral range can cover all requirements, from development over clinical batch production for scale-up trials to large scale production for marketed products.