For decades, when flash freezing was not an option the preferred method for fresh tissue collection and protection has been the use of products like RNAlater® to protect the RNA at room temperature. Now there is a better alternative. GenTegra RNAdvantage provides significantly better protection for the RNA in tissues using RIN values as a measure of RNA quality.
RNAdvantage consistently yields RNA with RIN scores that are ≥ 1 better than RNAlater. More importantly the RIN values when using RNAdvantage are at or above the desired RIN value of ≥7, ensuring excellent RNAseq results. Why risk having your RNA extraction rejected for RNAseq because the RIN number is too low? By using RNAdvantage, your RIN values will meet or exceed the recommended RIN number for excellent RNAseq data.
Using GenTegra RNAdvantage is identical to how you use RNAlater. RNAdvantage can be substituted for RNAlater with no changes to your current protocol. The only difference will be that your RIN values for the RNA will be on average 1 RIN number greater. Your RNA will be better protected and ensures your RNA is suitable for RNAseq at all sequencing services, commercial or university core labs.
Benefits
RIN values ≥ 7 for most tissues
Rapid RNase inactivation
Best protection at 7 and 14 days at RT
No rtPCR or library prep inhibition
Ensures reliable RNAseq data
Makes field collection of tissue samples easier
Virtually guaranteed excellent RNAseq results
University core sequencing facilities often have more stringent requirements on the RIN number for RNA being submitted for RNAseq.