Solution reagent YST0075 series

NGSFFPE tissuesfor ERBB2 gene

TargetPlex FFPE-Direct NGS 78-Gene Cancer Hotspot Panel – Primer Pool was designed to target 78 oncogene or tumor suppressor genes with a total of 378 amplicons in three-primer pools(5x). The primers are designed with the innovative TargetPlex noise-canceling technology to enhance sequencing efficiency improve detection sensitivity down to 1% allelic frequency. This product contains only the TargetPlex primer pool and requires the TargetPlex Library Prep Kit catalog (Illumina compatible) or the catalog (Ion Torrent compatible) kits to complete the library. Gene list: ( )=number of amplicons AKT1 (1), AKT2 (1), AKT3 (3), ALK (7), APC (10), AR (2), ARAF (1), ARID1A (9), BAP1 (8), BRAF (3), BRCA1 (2), BRCA2 (2), CDH1 (4), CDK4 (1), CDKN2A (3), CSF1R (2), CTCF (8), CTNNB1 (1), DDR2 (1), ERBB3 (6), ERBB4 (5), ESR1 (4), FAT1 (2), FBXW7 (10), FGFR3 (5), FOXL2 (1), GATA3 (2), GNA11 (2), GNAQ (2), H3F3A (1), HIST1H3B (1), HNF1A (9), IDH1 (1), IDH2 (2), JAK2 (3), KDR (10), KEAP1 (1),KIT (15),KMT2C (2),KMT2D (4),KRAS (3), MAP2K1 (7), MAP2K2 (1), MAP3K1 (3), MLH1 (1), MTOR (4), NF1 (4), NFE2L2 (2), NOTCH1 (8), NRAS (4), PDGFRA (4), PIK3CA (11), PIK3R1 (8), POLE (2), PTEN (23), RAC1 (3), RB1 (5), RET (7), RHOA (3), ROS1 (2), SF3B1 (5), SMAD4 (7), SMARCB1 (4), SMO (4), SRC (1), STK11 (22), TP53 (23), TSC1 (1), TSC2 (2), U2AF1 (2), VHL (3)