Solution reagent Go-DOAC™
for hematologyfreeze-driedthrombin

Solution reagent - Go-DOAC™ - Haematex - for hematology / freeze-dried / thrombin
Solution reagent - Go-DOAC™ - Haematex - for hematology / freeze-dried / thrombin
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Characteristics

Type
solution
Applications
for hematology
Format
freeze-dried
Tested parameter
thrombin, factor VIII
Method
chromogenic
Storage temperature

Min.: 2 °C
(36 °F)

Max.: 8 °C
(46 °F)

Description

Go-DOAC™ is a simplified clotting test with high sensitivity for all new DOACs (including dabigatran, apixaban, rivaroxaban and edoxaban). DESCRIPTION: Go-DOAC™ test reagent is a modified phospholipid-rich Russells viper venom reagent with enhanced sensitivity to DOACs. Go-DOAC™ is resistant to most lupus inhibitors and heparins (up to 1u/ml) but is sensitive to warfarin and defects in the common coagulation pathway. New or direct oral anticoagulants (DOACs) include inhibitors of thrombin (eg. dabigatran) and factor Xa (eg. rivaroxaban, apixaban and edoxaban). The latter group are difficult to quantitate using current clotting methods and expensive chromogenic assays for the individual agents are in use. ​The lupus anticoagulant-resistant dilute Russells viper venom test (dRVT-LR or "Confirm") has been suggested as a possible test method for all the DOACs since it is very sensitive to both classes of these inhibitors in vitro and in vivo and is less affected by extraneous variables such as heparins or low factor VIII levels than other clotting tests. ​We guarantee a competitive price for our reagents. ​Also available in bulk powders, please contact us for further information.

Catalogs

Go-DOAC™
Go-DOAC™
3 Pages
*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.