FDSS/μCELL is a laboratory screening system that compactly integrates technologies developed in drug discovery screening, enabling a purpose-built system that is simple to use.
Simultaneous measurement and analysis of the kinetics of a sample’s fluorescence or luminescence intensity in all wells at the time of compound addition are made possible by the high sensitivity two-dimensional sensor (camera) and dispenser head (96 tip type / 384 tip type). Screening various compounds at high throughput is enabled by measurement under the same conditions with no time lag between wells.
Features
Suitable for fluorescence / luminescence analysis
Simultaneous addition and reading in 96 wells / 384 wells
Enables a wide range of measurements with excitation light sources of various wavelengths
Long life, high power LED excitation light source
Suitable for FRET or BRET by changing wavelength
High speed data capture of 5 ms maximum (optional)
Simultaneous electrical stimulation and reading in 96 wells (optional)
External control option available for automation (optional)
Temperature can be maintained at +35 ºC to +37 ºC by installing heater unit (optional)
CO2 incubation (optional)
Waveform analysis (optional)
Applications
GPCRs (G protein-coupled receptors) play a major role in cell signaling, and many GPCR-targeted medical drugs have been developed. FDSS/μCELL is capable of detecting messengers, such as Ca2+ and cAMP, which are major contributors to the GPCR signaling system by using fluorescence and luminescence probes.
Specifications
Dispense (96-tip type) A10118-24 - 10 μL to 200 μL
Dispense (384-tip type) A10118-26 - 1 μL to 30 μL