Monkeypox virus Antigen Test Kit (Immunochromatography) is a solid phase immunochromatographic assay for the rapid, qualitative detection of antigen to Monkeypox virus in human body fluid. This test provides only a preliminary test result. Therefore, any reactive specimen with the Monkeypox virus Antigen Test Kit (Immunochromatography)must be confirmed with alternative testing method(s) and clinical findings.
Introduction
Monkeypox is a viral zoonosis (a virus transmitted to humans from animals) with symptoms very similar to those seen in the past in smallpox patients, although it is clinically less severe. With the eradication of smallpox in 1980 and subsequent cessation of smallpox vaccination, monkeypox has emerged as the most important orthopoxvirus for public health. Monkeypox primarily occurs in Central and West Africa, often in proximity to tropical rainforests and has been increasingly appearing in urban areas. Animal hosts include a range of rodents and non-human primates.
Principle
Monkeypox virus Antigen Test Kit (Immunochromatography) is a colloidal gold immunochromatographic assay.lt detects the virus Antigen of Monkeypox virus.
The test uses Monkeypox virus antibody (test line T) and goat anti-mouse IgG (control line C) immobilised on a nitrocellulose strip. The burgundy colored conjugate pad contains colloidal gold conjugated to another Monkeypox virus antibody conjugated with colloid gold and mouse IgG-gold conjugates. When the processed buffer containing the sample is added to the sample well, Monkeypox virus will combine with the Monkeypox virus antibody conjugate to form an antigen-antibody complex.