Powder hemostatic agent MPH

ENT surgerycardiovascular surgeryneurosurgery

Surgiclean® Absorbable Hemostatic Particles (Here after called Surgiclean® ) are spherical or ellipsoidal microporous microspheres with spatial reticular microstructure, good biocompatibility, and diameter of 30.8μm-97μm, prepared with potato starch as the raw materials using the emulsification and crosslinking technology; they are aseptic and pyrogen-free, and contain no components of animal origin or human origin; they are packaged in polyethylene sprayers sealed by screw caps, conditioned in a blister of PVC, sterilized with ethylene oxide and finally packaged into carton box. Surgiclean® have the function of a hydrophilic molecular sieve, can absorb and lock the water several times over weighting themselves instantly to form gels, and form gel mixtures around particles by condensing visible components in the blood outside the gels, such as platelets, red blood cells, albumins, thrombin and fibrinogen, thus promo ting instant clot forming; in addition, the blood at the bleeding sites is concentrated rapidly, thus resulting in concentration of platelets, initiating the coagulation mechanism, and accelerating the natural coagulation; Surgiclean® apply certain pressure on the peripheral vessel to promote the hemostasis after absorbing water and expanding; Surgiclean® form waterproof gels after absorbing water, and the polysaccharide particles can block off the wounds and promote the blood coagulation. Surgiclean® hemostatic microsphere degradation in the bodies initiates after hemostasis and finishes within 14 days. The Surgiclean® are decomposed into maltose and glucose by amylase andα-glucoside to form water and carbon dioxide finally,