This large sterilizer uses the saturated vapor under high pressure as sterilizing agent supplied from the external steam generator to sterilize a large number of medical instruments or bulky packages at a time, and has the excellent vacuum performance, durability and low noise by powerful vacuum system which is comprised of the water ejector, water pump and heat exchanger. The control system, which is the brain of sterilizer, shall be managed quickly to prevent trouble for medical affairs in case of occurring failure, therefore it is designed to be a compact component type that is capable of separating and assembling, and operator can separate the failed from the sterilizer and change it with a prepared normal one easily. The cycle processing of standard type sterilizer is fully automated by the control system (CTL-1000) and able to monitor it on the LCD, the door is manual or power driven type and operated by the function keys on the control panel, the door opening/closing mechanism is the radial lever type and it's chamber sealing function is excellent. If the power door is broken down or power failure, the door could be operated manually by using the hand-wheel without any tools or procedure. The optional type sterilizer adopted a wide touch screen color LCD is fully automated by the exclusive control system (CTL-1000TS2), and able to operate the sterilizer on the touch screen, to monitor the cycle processing in real time and to manage the sterilizer by one touching on it. The door is divided into 4 types such as manual or power driven type and double or single door type, it could be operated and controlled on the touch screen LCD conveniently.