Heart organ perfusion system IH-5

isolated

The IH-5 Langendorff Core System is the starting point for all isolated perfused heart experiments for medium-sized rodents (rat, guinea pig and rabbit) in the Langendorff retrograde perfusion mode. The Core System contains all the primary equipment to accomplish the basic Langendorff experiment. A fully functional IH-5 Langendorff System requires the addition of core system options and other components including: Method of constant pressure perfusion Species-specific additions (cannulae, buffer reservoirs and balloons) Heart chamber Desired data acquisition system The modular nature of the IH-5 allows the system to evolve along with your research. Our Langendorff System can easily be upgraded to a full working heart system according to Neely, accommodating aortic flows up to 500 ml/min or to a biventricular working heart system where both sides of the heart eject fluid as in vivo. Other options add additional measurement and application capabilities, such as multi-channel ECG and MAP cardiac electrophysiology applications. Advanced System Design The IH-5 utilizes the architecture of the ground-breaking IH-SR to set the standard for isolated heart perfusion in rabbits, adult guinea pigs, or adult rats. Engineered for the increased flow produced by these species (up to 500 mL/min), the IH-5 offers ultimate perfusion stability and real physiological conditions for longer, more relevant recordings with fewer artifacts. This compact platform has been optimized to create in situ-like perfusion features, delivering a considerably higher sensitivity for various experimental manipulation while maintaining the advantages of an ex vivo preparation.