BRAF gene mutation detection can be used to assist the diagnosis and classification of thyroid carcinoma, and to assist the clinicians to assess the prognosis of BRAF gene targeted drugs such as Vemurafenib for melanoma patients, Erbitux (cetuximab) and vectibix (panitumumab) for colorectal cancer patients.
Key Features
Detection principle: Real-time PCR with ARMS primers.
Detection characteristics: detection of mutation of locus V600E in BRAF gene exon 15.
Sensitivity: it can detect 1% or even lower content of BRAF mutation gene.