HUBI LH is an in-vitro diagnostic test based on immunochromatography. The test is required to be applied to HUBI QUAN pro, an analyzer designed for quantitative détermination of Luteinizing Hormone (LH) in human blood specimens.
Luteinizing Hormone (LH) is secreted by the anterior pituitary grand. It secreted only a little amount during most of menstrual cycle. But it suddenly increases for short time in the middle part of cycle. This increase is called the LH surge and it triggers ovulation. In maies, where LH had also been called interstitial cell-stimulating hormone (ICSH), it stimulâtes Leydig cell production of testosterone. LH is a glycoprotein hormone having two subunits
(alpha-, beta-). Its structure is similar to that of the other glycoprotein hormones, Follicle Stimulating Hormone (FSH), Thyroid-Stimulating Hormone (TSH), and human Chorionic Gonadotropin (hCG).
In both maies and females, LH is essential for reproduction. In females, FSH initiâtes follicular growth, specifically affecting granulosa cells. With the rise in estrogens, LH receptors are also expressed on the maturing follicle, which causes it to produce more estradiol. As the follicle matures, the secreted of estrogen is regulated by‘positive feed -back’in the hypothalamus. At this time, LH is secreted for 24 to 48 hours. This ‘LH surge’ triggers ovulation.