The Monkeypox virus IgG/IgM Rapid test is a rapid chromatographic immunoassay for the qualitative detection of IgG and IgM antibodies to Monkeypox virus in human whole blood, serum, or plasma as an aid in the diagnosis of Monkeypox infections.
Benefits
• Facilitates patient treatment decisions quickly
• Simple, time-saving procedure
• All necessary reagents provided & no equipment needed
• High sensitivity and specificity
Principle
The Monkeypox virus IgG/IgM Rapid test is a qualitative membrane-based immunoassay for the detection of Monkeypox antibodies in whole blood, serum, or plasma. This test consists of two components, an IgG component and an IgM component. In the IgG component, anti-human IgG is coated in test line region G of the test. During testing, the specimen reacts with Monkeypox antigen-coated particles in the test strip. The mixture then migrates upward on the membrane chromatographically by capillary action and reacts with the anti-human IgG in test line region G. If the specimen contains IgG antibodies to Monkeypox, a colored line will appear in test line region G. In the IgM component, anti-ligand is coated in test line region M of the test. During testing, the specimen reacts with ligand anti-human IgM. Monkeypox IgM antibodies, if present in the specimen, reacts with the ligand anti-human IgM and the Monkeypox antigen-coated particles in the test strip, and this complex is captured by the anti-ligand, forming a colored line in test line region M. Therefore, if the specimen contains Monkeypox IgG antibodies, a colored line will appear in test line region G.