Challenges in access to quantitative imaging can impact neurocritical care. The Radiological Society of North America defines quantitative imaging as the extraction of quantifiable features from medical images for the assessment of normal or the severity, degree of change, or status of a disease, injury, or chronic condition relative to normal. Due to limited access to neuroimaging, a challenge in neurocritical care is obtaining quantitative imaging biomarkers, such as midline shift1.
Midline shift is the amount of displacement of the brain’s midline from its normal symmetric position. It is an essential quantitative biomarker for clinicians to assess the severity of brain injury and signify neurological damage after stroke. Identifying midline shift, especially with early or subtle onset, can significantly improve patient outcomes. In emergency situations, it is not always a neuro-specialist taking the first look at the study. Automated midline shift measurement would provide value to nonspecialists, especially those who read images in emergency situations2.
Another imaging biomarker calculation is ventricular volume measurements, which quantifies the cerebrospinal fluid within the ventricles. Ventricular volume has relevance for many neurological conditions and has demonstrated utility in managing conditions such as hydrocephalus. Changes in ventricular size and shape can help clarify a patient’s clinical status and thus guide neurosurgical decision-making3.