Synthetic bone substitute BioRestore™

for orthopedic surgerygranules

Inion BioRestore™ is made of degradable bioactive glass, which once in contact with the natural body fluids forms a silica gel and calcium phosphate layer, providing scaffolding for the new bone tissue to be formed. Inion BioRestore™ is a CE-marked medical device (Class III), manufactured by Inion Oy. The conformity assessment was conducted by BSI The Netherlands (CE 2797). Benefits of Inion’s synthetic bone graft substitute Complete degradation: Inion BioRestore™ bone graft substitute is gradually resorbed and replaced by new bone within 6 months in vivo. The highly porous and fully open structure, composed of fibers welded together, enables better flow of fluid, cells and nutrients and allows formation of new bone throughout the structure, inside and out. Controlled and significantly faster resorption and replacement by bone compared to other commercially available products (e.g. HA and other bioactive glass products). Osteoconductive and osteostimulative: Inion BioRestore™ actively stimulates osteoblast proliferation and differentiation while providing a scaffold to support new bone formation. Antibacterial: Scientific studies have shown that the bioactive glasses have antibacterial properties which may inhibit the occurrence of bacterial infection at the surgical site. Biocompatible, safe and easy to use: Synthetic origin shortens operative time and excludes risks of disease transmission and overcomes the limitations in quantity and quality of available bone grafts.