Thrombophilia is a term used to describe conditions where the tendency to clot in the blood is increased, and therefore the risk of venous thromboembolism (VTE) is high.
Acquired and hereditary factors play a role in its etiology.
Causes of acquired thrombophilia (age, obesity, smoking, etc.) and/or changes in many genes that play a role in the fluidity of the blood in the blood vessels affect the system towards the formation of thrombosis.
Thrombosis is among the most common causes of death in the world.
INOGene-Cardiovascular Disease 6 (FII, FVL, MTHFR677, 1298, FXIII, PAI) Panel Real-Time PCR Kit provides detection of mutations in Factor V, Prothrombin Factor II, MTHFR, Factor XIII and Serpine1 (PAI-1) genes in human biological samples.
It is a medical in vitro diagnostic kit based on Melting curve anaysis via Real Time PCR instrument.
Nucleic acid extraction can be performed from whole blood samples in EDTA tubes with any commercial DNA isolation/extraction kits.