Bovine pericardium dural substitute DuraGen® Classic

The DuraGen matrices have been engineered to balance strength and flexibility ensuring optimal handling, enhanced contact, and resportion - leaving the patient with a natural dural repair. DuraGen® dural graft is one of the safest and most effective onlay grafts for the restoration and repair of dura mater. • DuraGen is made from a controlled collagen source and is treated with a proprietary process designed to remove antigenic components, yielding our Ultra Pure Collagen™. It is conformable and contours instantly and effectively to the complex surfaces of the brain and spinal cord, rapidly forming a biological seal to protect against CSF leakage. • Integra pioneered regenerative medicine. • Over 10 million collagen implants. • Integra created the onlay dural graft paradigm. How DuraGen Works The onlay nature of DuraGen revolutionized duraplasty. • The highly porous collagen scaffold promotes rapid fibrin clot formation. • DuraGen rapidly provides watertight closure to prevent CSF leakage while promoting natural dural growth. It Starts with Ultra Pure Collagen™ Limits the risk of infection, immunological response, and foreign body reaction. Precisely Engineered Porosity Allows rapid fibrin clot formation to stop CSF leakage and facilitates uniform tissue regeneration throughout the matrix. Excellent Conformability and Handling Provides intimate graft contact with dural margins to keep the graft in place without suture and to reduce leakage. Dural Regeneration Matrix The original onlay dural regeneration graft. • Extensively clinically studied.