T experiment maze Zebrafish

for animal research

The MazeEngineers Zebrafish T maze allows for choice experiments. Arms are baited with colors or cues and zebrafish are allowed to make choices in experiments. Enrichment boxes can be added to allow for stimuli to drive these choices. Multiple sizing and shapes available. Drain provided upon request alacarte and can be lifted from the ground or table to allow for easy drainage. Introduction The T-maze is an operant task widely used in multiple species. In zebrafish, the T-maze has been used to study color discrimination (Colwill et al., 2005, Avdesh et al., 2012), memory (Braida et al., 2014, Echevarria et al., 2016), locomotion and exploratory behavior (Peitsaro et al., 2003, Vignet et al., 2013), and place preference (Swain et al., 2004). Previous reports have shown that zebrafish exhibit long-term retention of spatial alternation (Williams et al., 2002) and active avoidance learning (Pradel et al., 1999) to color discrimination learning. Therefore, zebrafish display rapid and reliable conditioning well-suited for neurobehavioral tests. The test requires a Plexiglas T-maze with variable configurations and sizes. Diverse protocols can be followed, including assessment of visual discrimination using colored or patterned sleeves in a designated goal zone or enrichment chamber in the arm of the maze. The investigator can use positive reinforcement with food rewards or environmental enrichment in the goal zone. Experimental protocols typically entail measuring time to reach the goal zone or variation of percentage of correct choices to assess learning, or discrimination between pairs of visual stimuli.