This kit is used for qualitative typing detection of denguevirus (DENV) nucleic acid in suspected patient’s serum sample to help diagnose patients with Dengue fever. The test results obtained by the kit are for clinical reference only. The final diagnosis results must be combined with the clinical manifestations of patients and other laboratory tests to conduct a comprehensive analysis of the disease condition.
Dengue fever (DF), which is induced by denguevirus (DENV) infection, is one of the most epidemic arbovirus infectious diseases. Its transmission medium includes Aedes aegypti and Aedes albopictus. DF is mainly prevalent in tropical and subtropical areas. DENV belongs to flavivirus under flaviviridae, and can be classified into 4 serotypes according to surface antigen. Clinical manifestations of DENV infection mainly include headache, fever, weakness, enlargement of lymph node and leukopenia, etc., and bleeding, shock, hepatic injury or even death in severe cases. In recent years, climate change, urbanization, quick development of tourism and other factors have provided more rapid and convenient conditions for transmitting and spreading of DF, leading to constant expansion of epidemic area of DF. Therefore, establishment of easy, specific and rapid etiological diagnosis method of DENV has important significance for clinical diagnosis of DF.