This kit is used for in vitro qualitative detection of monkeypox virus nucleic acid in human rash fluid, nasopharyngeal swabs, throat swabs and serum samples.
Epidemiology
Monkeypox (MP) is an acute zoonotic infectious disease caused by Monkeypox Virus (MPV). The disease is mainly transmitted by animals, and humans could become infected by being bitten by infected animals or by direct contact with the blood, body fluids and rash of infected animals. The virus can also be transmitted between people, primarily through respiratory droplets during prolonged, direct face-to-face contact or through direct contact with a patient’s body fluids or contaminated objects.
The clinical symptoms of monkeypox infection in humans are similar to those of smallpox, generally after a 12-day incubation period, appearing fever, headache, muscle and back pain, enlarged lymph nodes, fatigue and discomfort. The rash appears after 1-3 days of the fever, usually first on the face, but also in other parts. The disease course generally lasts 2-4 weeks, and the mortality rate is 1%-10%. Lymphadenopathy is one of the main differences between this disease and smallpox.
Technical Parameters
Storage - Liquid: ≤-18℃ In dark; Lyophilized: ≤30℃ In dark
Shelf-life - 12 months
Specimen Type - Rash Fluid, Nasopharyngeal Swab, Throat Swab, Serum
Ct - ≤38
CV - ≤5.0%
LoD - 200Copies/mL
Specificity -
No cross-reactivity with Smallpox virus, Cowpox virus, Vaccinia virus, Herpes simplex virus, etc. No cross-reactivity with other pathogens that cause rash disease. No cross-reactivity with human genomic DNA.
Applicable Instruments -
It can match the mainstream fluorescent PCR instruments on the market.