Short Description:
This kit is used for in vitro qualitative detection of Klebsiella pneumoniae (KPN), Acinetobacter baumannii (Aba), Pseudomonas aeruginosa (PA) and four carbapenem resistance genes (which include KPC, NDM, OXA48 and IMP) in human sputum samples, to provide the basis of guidance of clinical diagnosis, treatment and medication for patients with suspected bacterial infection.
Epidemiology
Klebsiella pneumoniae is a common clinical opportunistic pathogen and one of the important pathogenic bacteria causing nosocomial infections. When the body's resistance is reduced, the bacteria enter the lungs from the respiratory tract, causing infection in multiple parts of the body, and the early use of antibiotics is the key to cure [1].
The most common site of Acinetobacter baumannii infection is the lungs, which is an important pathogen for Hospital acquired pneumonia (HAP), especially Ventilator associated pneumonia (VAP). It is often accompanied by other bacterial and fungal infections, with characteristics of high morbidity rate and high mortality rate.
Pseudomonas aeruginosa is the most common non-fermentative gram-negative bacilli in clinical practice, and is an important opportunistic pathogen for hospital-acquired infection, with the characteristics of easy colonization, easy variation and multi-drug resistance.
Channel
Name - PCR-Mix 1 - PCR-Mix 2
FAM Channel - Aba - IMP
VIC/HEX Channel - Internal Control - KPC
CY5 Channel - PA - NDM
ROX Channel - KPN - OXA48
Technical Parameters
Storage -
≤-18℃
Shelf-life - 12 months
Specimen Type - Sputum