Intended Use
The kit is used for in vitro quantitative detection of the concentration of progesterone (Prog) in human serum, plasma or whole blood samples.
Epidemiology
Prog is a type of steroid hormone with a molecular weight of 314.5, mainly produced by the corpus luteum of the ovaries and the placenta during pregnancy. It is a precursor to testosterone, estrogen, and adrenal cortex hormones. Prog can be used to determine whether the corpus luteum function is normal. During the follicular phase of the menstrual cycle, Prog levels are very low. After ovulation, Prog produced by the corpus luteum rapidly increases, causing the endometrium to transition from a proliferative state to a secretory state. If not pregnant, the corpus luteum will shrink and the concentration of Prog will decrease in the last 4 days of the menstrual cycle. If pregnant, the corpus luteum will not wither and will continue to secrete Prog, keeping it at a level equivalent to mid luteal phase and continuing until the sixth week of pregnancy. During pregnancy, the placenta gradually becomes the main source of Prog, and Prog levels increase.
Technical Parameters
Target region
Serum, plasma, and whole blood samples