ELISA kit

for liver diseasebloodserum

Human sialic acid glycoprotein receptor (ASGPR) is expressed only in hepatocytes and is responsible for the removal of sialic acid glycoprotein from plasma. ASGPR consists of two related amino acid sequence subunit H1(46 KD) and H2(50 KD), H2a and H2b H2 subunits are two variable shears. H2a and H2b differ only in the extra pentapeptide structure in the outer cytoplasmic domain adjacent to the transmembrane fragment, Research shows, H2a cleaved to 35 KD next to pentapeptide, Including the complete extracellular domain, For secretory purposes, soluble form (sH) of constituent receptors 2 a). [Intended use] This product can assist in the diagnosis of liver injury diseases such as fatty liver, alcoholic liver, drug-induced hepatitis, autoimmune hepatitis, viral hepatitis, cirrhosis and so on by detecting sH2a levels of soluble forms in serum. [Product Advantage] The information of liver function can be obtained by detecting the sH2a content in the blood of patients. It can be used as auxiliary diagnosis of viral hepatitis, liver fibrosis, liver cirrhosis, liver cancer and monitoring the course of liver cancer. sH2a quantitative test kit can stably and accurately detect the content of sH2a in human serum. Pre-clinical studies have found that sH2a in patients with liver injury and liver cancer. The content is higher than that of healthy people, the sH2a content of liver cancer patients is higher than that of liver injury patients; the change of serum sH2a level will change with the change of liver cancer patients' condition and give clinical guidance to doctors and patients.