Colorectal cancer test kit

bloodplasmafor PCR

Septin is a conserved skeleton protein gene family with GTPase activity widely distributed in all eukaryotes except plants, and is related to cell division. In humans, it consists of 14 family members, named Septin1~14, respectively, of which Septin9 is located at 17q25.3, contains 17 exons, and encodes Septin9 protein, which has multiple subtypes (such as Septin 9-vl, v2). , V3, v4,), and each subtype has structural similarity. It consists of the central P-loop GTP binding domain, variable N-terminal and C-terminal domains, which are separated from chromosomes, DNA repair, migration, and apoptosis. Death and other cell functions. Studies have found that Septin9 is directly related to the occurrence of tumors and its expression and function are not the same in different tumors. In colorectal cancer, the CPG island of the Septin9-v2 promoter region is highly methylated. 【expected usage】 It is used for in vitro qualitative detection of Septin9 gene methylation in human peripheral blood plasma, which effectively improves the detection rate of early colorectal cancer and significantly improves the survival rate of patients. 【Product advantages】 Used for in vitro qualitative detection of Septin9 gene methylation in human peripheral blood plasma, using exclusive double-stranded detection technology, only 5ml of blood, matching the self-developed automatic nucleic acid extraction instrument, 3.5 hours to complete the detection,