Liver disease test kit

bloodserum

The human sialoglycoprotein receptor (ASGPR) is only expressed in liver cells and is responsible for the clearance of asialoglycoprotein from plasma. ASGPR consists of two related amino acid sequence subunits H1 (46KD) and H2 (50KD). H2a and H2b are the two alternative splice variants of the H2 subunit of ASGPR. H2a and H2b differ only in the structure of the extra pentapeptide in the extracytoplasmic domain next to the transmembrane fragment. Studies have shown that H2a is cleaved into a 35KD fragment next to the pentapeptide, including the complete extracellular domain, which is secretory. The soluble form of the receptor (sH2a). 【expected usage】 The level of soluble form of sH2a in the serum can be detected to assist in the diagnosis of liver injury diseases such as fatty liver, alcoholic liver, drug-induced hepatitis, autoimmune hepatitis, viral hepatitis, and cirrhosis. 【Product advantages】 By detecting the level of sH2a in the blood of patients, information on liver function status can be obtained, which can be used as an auxiliary diagnosis of viral hepatitis, liver fibrosis, cirrhosis, liver cancer and monitoring of the course of liver cancer. The sH2a quantitative detection kit can stably and accurately detect the level of sH2a in human serum. Preclinical studies have found that the level of sH2a in patients with liver injury and liver cancer is higher than that in healthy people, and the level of sH2a in patients with liver cancer is higher than that in patients with liver injury;