MTHFR (C677T) DNA qPCR Detection Kit
MTHFRis the key enzyme in the folate metabolism, its gene polymorphism can lead tothe decrease of the key enzyme activities in folate metabolism and cause thedisorder of folic acid metabolism, which leads to many diseases. In addition,the MTHFR polymorphism affects the therapeutic effects of 5-FU and methotrexate(MTX).
The kitcan be used for the diagnosisof MTHFR (methylenetetrahydrofolate reductase) gene locus C677T polymorphism inhuman whole blood or human oral exfoliated cells.
32 Reactions/Kit
Applicable Instrument
ABI 7500 Real-Time PCR System, SLA96 or Gentier96
Samples
Human EDTA anticoagulant whole blood, human sodium citrateanticoagulant whole blood, or human oral exfoliated cell.
Pathogens
Assay for the detection of MTHFR
Methods
Multiplex qPCR method, Taqman fluorescent probe technology
Detection
MTHFR C677T gene site
Three genotypes: CC, CT and TT
Indications
Diseases caused by MTHFR (C677T)
Assay
One-tube premix
Results
Automatic data reports
Efficiency
Real-time
High-accuracy
Indexes
Coincidence rate: 100%
Variation coefficient: less than 5%
No cross reactions