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Genetic mutation test kit
for DNAwhole bloodfor DNA

genetic mutation test kit
genetic mutation test kit
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Characteristics

Applications
for genetic mutations
Tested parameter
for DNA
Sample type
whole blood, for DNA
Analysis mode
for qPCR

Description

MTHFR (C677T) DNA qPCR Detection Kit MTHFRis the key enzyme in the folate metabolism, its gene polymorphism can lead tothe decrease of the key enzyme activities in folate metabolism and cause thedisorder of folic acid metabolism, which leads to many diseases. In addition,the MTHFR polymorphism affects the therapeutic effects of 5-FU and methotrexate(MTX). The kitcan be used for the diagnosisof MTHFR (methylenetetrahydrofolate reductase) gene locus C677T polymorphism inhuman whole blood or human oral exfoliated cells. 32 Reactions/Kit Applicable Instrument ABI 7500 Real-Time PCR System, SLA96 or Gentier96 Samples Human EDTA anticoagulant whole blood, human sodium citrateanticoagulant whole blood, or human oral exfoliated cell. Pathogens Assay for the detection of MTHFR Methods Multiplex qPCR method, Taqman fluorescent probe technology Detection MTHFR C677T gene site Three genotypes: CC, CT and TT Indications Diseases caused by MTHFR (C677T) Assay One-tube premix Results Automatic data reports Efficiency Real-time High-accuracy Indexes Coincidence rate: 100% Variation coefficient: less than 5% No cross reactions
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