This product uses fluorescence immunochromatography to quantitatively detect the content of cNT-proBNP in serum/plasma. Basic principle: T and C lines are respectively marked on the nitrocellulose membrane, and the T line is coated with an antibody a that specifically recognizes cNT-proBNP. The binding pad is sprayed with another fluorescent nano-material-labeled antibody b that can specifically recognize cNT-proBNP. The cNTproBNP in the sample first combines with the nano-material-labeled antibody b to form a complex, which is then chromatographed upwards. The T-line antibody a binds to form a sandwich structure. When the excitation light is irradiated, the nanomaterial emits a fluorescent signal, and the strength of the signal is positively correlated with the concentration of cNT-proBNP in the sample.
Detailed
【Detection purpose】 Canine N-terminal pro-brain natriuretic peptide(Canine NT-proBNP)is a substance secreted by myocardial cells in the canine ventricle, which can be used as a detection indicator for corresponding heart failure. The concentration of cNT-proBNP in the blood is related to the severity of the disease. Therefore, NT-proBNP can not only assess the severity of acute and chronic heart failure, but also serve as an indicator of its prognosis.