Unlike classic wet granulation methods, this process does not require any energy-intensive drying processes; this avoids the need for large investments in systems and production facilities, and lowers the costs per batch.
L.B. Bohle’s BRC granulators are suitable for continuous production and can be integrated with Process Analytical Technology (PAT). Because of this, the BRC series granulators offer flexibility for integration into a wide variety of production scenarios.
L.B. Bohle combines high product capacity with minimal material loss in dry granulation. This system outclasses rival solutions by generating force through purely electromechanical means to ensure consistent ribbon properties The BRC uses highly innovative methods to regulate compacting force and ribbon thickness. It compacts material uniformly over a production range of
< 1 - 400 kg/h. The sophisticated system design facilitates handling and shortens the assembly process. The hygienic design and the integrated washer nozzles, fitted as standard, allow for an effective WIP process.
Even at high material throughputs, the cone-shaped BTS Bohle Turbo Sieve mill and sieve inserts gently crush the ribbons into granules with the desired particle size distribution. Each BRC dry granulator can be retooled with a different rotary sieve within minutes to adjust to new process and ribbon requirements.
Thanks to its functional GMP-compliant design and PAT tool support, the compactor meets the requirements of the pharmaceutical “Quality by Design”.