High-shear granulator GMA

for the pharmaceutical industryR&D

High-shear granulators have been successfully used by the pharmaceutical industry for decades as a shaping method for granulation. With high-shear granulation, a binding fluid is added to the powdery particles in a closed tank that has an agitator blade and chopper. The agitator blade with its high-shear and compaction guarantees effective granulation. Dense granules are formed. The chopper prevents excessive granule growth and distributes the granulation fluid throughout the product. L.B. Bohle’s high-shear granulation portfolio includes R&D systems for small production volumes as well as production-scale systems. The GMA high-shear granulator system has been specially optimized for pharmaceutical applications and is designed for through-the-wall mounting. The core of the GMA granulator is the cylindrical process bowl with double dished heads. The shape of the tank in combination with the agitator blade geometry ensures an effective granulation. The bowl connects to the head section via electrically driven lifting cylinders, which allows it to be lowered down, i.e. for inspections. The GMA granulation system works with up to 12 bar and is pressure-surge-resistant. The pressure-surge-resistant version features extremely strong tank lifting spindles that keep the tank sealed even in the event of an accident. The head section also has a filler neck for gravity feeding. The switch cabinet is also located directly on the machine – at the rear. - Low fluid consumption - Easy discharge - closed system - Granulation can be controlled according to time, quantity or output - Easy to clean and complete draining of water